Despite its impact on increasing survival, the tumor and its treatment can cause significant side effects. Your healthcare team can speak with you about the potential side effects of your/your child’s personalized treatment plan, and help you weigh risks against the benefits. Some of the more common effects are discussed here. In a recent study, about 25% of children undergoing surgery for their tumor developed delayed onset (usually 6 to 24 hours after awakening) loss of speech which was often associated with decreased muscle tone, unsteadiness, emotional lability, and irritability. This syndrome, called “posterior fossa mutism … Selanjutnya
Chemotherapy uses powerful drugs to kill cancer cells. For children with medulloblastoma, chemotherapy is used to reduce the risk of tumor cells spreading through the spinal fluid. For adults, this benefit is not quite as clear since their tumors tend to regrow in the cerebellum. Because different drugs are effective during different phases of a cell’s life cycle, a combination of drug may be given. The combination increases the likelihood of more tumor cells being destroyed.
Chemotherapy is now a standard part of treatment for children with medulloblastoma. Most children are treated in clinical trials — organized … Selanjutnya
Following surgery, medulloblastoma is usually treated with radiation therapy. It is an important “next-step” because microscopic tumor cells can remain in the surrounding brain tissue even after surgery has successfully removed the entire visible tumor. Since these remaining cells can lead to tumor regrowth, the goal of radiation therapy is to reduce the number of left-over cells. Doctors consider several factors in planning radiation therapy: The age of the patient, the location of the tumor, the amount of remaining tumor, and any tumor spread. Since radiating the brain and central nervous system can be damaging to a … Selanjutnya
If the tumor is determined to be a medulloblastoma, current treatment consists of surgically removing as much tumor as possible, followed by craniospinal (brain and spine) radiation and/or chemotherapy. Your doctor will suggest a treatment plan based on factors that indicate the risk of tumor recurrence — either “average-risk”
or “high-risk.” To determine risk, doctors look at the age of the patient; the amount of tumor remaining following surgery; and the amount of metastases, or tumor spread (also called M stage). Children are considered at “average-risk” of recurrence if they are diagnosed after age 3; if all, or nearly … Selanjutnya
Obtaining a symptom history and performing a neurological examination will be your doctor’s first steps in making a diagnosis. Magnetic resonance imaging (MRI), done both with and without a contrast dye, is then used to identify the presence of a tumor in the brain. The contrast dye is given intravenously (into the vein) to enhance the pictures. By concentrating in abnormal tissue, the dye makes a tumor appear much brighter than other areas. If a tumor suspected of being a medulloblastoma is identified, an MRI of the entire spine can be done to look for tumor in … Selanjutnya